WiQO
WiQo offers innovative and scientifically-backed products designed to address a wide range of skin concerns, from hydration and anti-aging to sensitivity and pore refinement.
PRX Plus
Non-invasive topical bio-stimulator for brighter, firmer, healthier skin
PRX Plus is a next-generation, non-peeling skin treatment designed to improve skin quality — texture, firmness and radiance — without traditional downtime. It harnesses a synergistic combination of clinically validated actives to stimulate the skin’s natural repair and rejuvenation pathways, delivering visible improvement in tone, elasticity and luminosity with a comfortable, quick in-clinic procedure.
PRX Plus is applied, not injected with little to no downtime and immediate results
What is PRX Plus?
PRX Plus is a professional aesthetic treatment formulated to support skin remodelling and surface renewal without aggressive epidermal exfoliation. Instead of relying on visible peeling to show results, PRX Plus works by stimulating deeper dermal processes — encouraging collagen and elastin activity while improving hydration and surface texture.
Ideal for patients who want noticeable skin quality improvements with minimal social downtime, PRX Plus is commonly used on the face, neck and décolletage and as an adjunct to other inclinic procedures.
Key ingredients
According to WiQo® (the manufacturer) and professional providers:
- 33% Ammonium Trichloroacetate (ATCA): A modified TCA derivative designed to stimulate the skin’s stress response and encourage fibroblast proliferation.
- Homocysteic Acid: A potent brightening agent that facilitates transfer of melanin into keratinocytes, aiding its natural shedding.
- Citric and Phytic Acids: Gentle exfoliants that help remove dead skin cells, providing a light resurfacing effect.
- Some product pages also specify homocysteic acid around 2% along with ATCA at 33%, and include citric and phytic acids as exfoliating boosters.
Mode of action — how PRX Plus works
1. Controlled dermal stimulation — The formulation reaches and interacts with dermal fibroblasts. This stimulates collagen and elastin production (a process often referred to as neocollagenesis and elastogenesis).
2. Modulation of superficial inflammation — The oxygenating/stabilising agent helps control the inflammatory cascade so the response is regenerative rather than destructive. This supports remodelling with reduced epidermal sloughing.
3. Improved hydration and barrier recovery — Hydrating excipients and barriersupporting agents help the skin recover more quickly and maintain an improved skin surface, reducing immediate tightness and flaking.
4. Cumulative enhancement with repeat sessions — Repeated treatments are believed to amplify fibroblast stimulation and extracellular matrix remodelling, leading to progressive improvements in skin tone, texture and laxity.
This combination — targeted dermal action with epidermal sparing — is what differentiates PRX Plus from conventional chemical peels and many purely topical rejuvenation products.
Mode of action — how PRX Plus works
1. Controlled dermal stimulation — The formulation reaches and interacts with dermal fibroblasts. This stimulates collagen and elastin production (a process often referred to as neocollagenesis and elastogenesis).
2. Modulation of superficial inflammation — The oxygenating/stabilising agent helps control the inflammatory cascade so the response is regenerative rather than destructive. This supports remodelling with reduced epidermal sloughing.
3. Improved hydration and barrier recovery — Hydrating excipients and barriersupporting agents help the skin recover more quickly and maintain an improved skin surface, reducing immediate tightness and flaking.
4. Cumulative enhancement with repeat sessions — Repeated treatments are believed to amplify fibroblast stimulation and extracellular matrix remodelling, leading to progressive improvements in skin tone, texture and laxity.
This combination — targeted dermal action with epidermal sparing — is what differentiates PRX Plus from conventional chemical peels and many purely topical rejuvenation products.
Safe for All Seasons
WiQo Professional Products are designed to be gentle and well-tolerated from all skin types all year-round, so they can be experienced even during the summer months.
Safe for All Skin Types
Whether your skin is dry, sensitive, acne-prone, or oily, our professional products are suitable for all skin types, Fitzpatrick and identities.
No peeling
Our solutions do not cause visible exfoliation, allowing to enjoy smooth-feeling skin without discomfort or downtime.
No needles
Achieve healthier-looking skin without invasive injections. Our needle-free solutions ensure a painless and comfortable experience.
15-Minute-Treatment
In just 15 minutes, it’s possible to experience an effective professional treatment, making it perfect to include in a regular skincare routine.
Immediate & Long-Lasting Effect
Notice instant improvements after your first treatment, with results that last, leaving your skin looking youthful and refreshed over time.
Clinical outcomes & what patients can expect
Clinical experience and practice outcomes have shown that PRX Plus can deliver the following improvements when administered by trained professionals and used as part of an evidencebased protocol:
- Improved skin texture — Smoother skin surface and reduced roughness after a course of treatments.
- Increased firmness and elasticity — Noticeable lift and improved skin resilience due to collagen remodelling.
- Enhanced radiance and evenness of tone — Brighter skin with reduced appearance of dullness and improved light reflection.
- Reduced appearance of fine lines and superficial wrinkles — Especially around delicate areas (perioral, periorbital) following multiple sessions.
- Adjunct benefits for scarring and stretch marks — When combined appropriately with other inclinic therapies, some clinicians report improvements in acne scarring and stretch marks.
Typical treatment course
- Most protocols recommend a series of sessions (commonly spaced 1–2 weeks apart) with maintenance treatments every few months depending on individual response and desired results.
- Each inclinic session is relatively quick (often 20–40 minutes depending on areas treated), and the procedure is usually described by patients as tolerable with little to moderate discomfort.
Downtime and side effects
- Because PRX Plus is designed as a nonpeeling biostimulatory treatment, visible downtime is minimal for most patients. Temporary redness, mild stinging or transient tightness may occur but typically resolves within hours to a couple of days.
- As with any professional skin procedure, proper pre and posttreatment care is essential to reduce the risk of complications and optimise outcomes.
Evidence & safety
PRX Plus is used by trained clinicians in medical aesthetic settings. Outcomes are supported by clinical case series and practitioner experience reporting improvements in skin quality with a favourable tolerability profile. As with any active professional treatment, the full safety profile depends on correct case selection, practitioner expertise and adherence to recommended protocols.
Important: Patients with active infections, open wounds, certain medical conditions, or a history of keloid scarring should be assessed carefully and may not be suitable candidates. Always consult a qualified practitioner for personalised medical advice.
Combination protocols (best practice)
PRX Plus is commonly and safely combined with other modalities.
This enhances results, for example:
This enhances results, for example:
- Microneedling or radiofrequency, to add mechanical/thermal stimulation to the matrix remodelling.
- Topical brightening and resurfacing products as part of a homecare regimen to prolong and enhance clinical results.
- Laser treatments — timed appropriately in treatment plans to maximise synergy while minimising risk.
Your clinician will tailor a protocol based on skin type, concerns and previous treatment history.
Patient journey & aftercare
1
Consultation
Assessment of skin type, medical history and realistic outcome setting.
2
Preparation
3
Treatment
Inclinic application by a trained clinician; typically 20–40 minutes.
4
Aftercare
Gentle cleansing, sunscreen and prescribed soothing/hydrating products. Avoid aggressive exfoliation for recommended period.
5
Follow-up
Review and scheduling of additional sessions if needed.
Frequently asked Questions (FAQs)
Is PRX Plus painful?
Most patients report only mild to moderate discomfort during application; no pain relief is necessary. Sensations are usually transient.
How soon will I see results?
Most patients report only mild to moderate discomfort during application; no pain relief is necessary. Sensations are usually transient.
Can it replace laser or injectables?
Most patients report only mild to moderate discomfort during application; no pain relief is necessary. Sensations are usually transient.
Book a consultation
Ready to improve skin quality with a modern, lowdowntime approach? Contact our clinic to book a consultation with a registered practitioner who can assess suitability and tailor a treatment plan.
This page is for informational purposes and does not replace personalised medical advice. Always consult a licensed clinician before starting any skin treatment.